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0 0.5 1 1.5 2+ Recovery time 40% Improvement Relative Risk Time to viral- 29% c19favipiravir.com Udwadia et al. Favipiravir for COVID-19 RCT EARLY Favors favipiravir Favors control
Udwadia, 150 patient favipiravir early treatment RCT: 40% faster recovery [p=0.03] and 29% faster viral clearance [p=0.13] https://c19p.org/udwadia
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Efficacy and Safety of Favipiravir, an Oral RNA-Dependent RNA Polymerase Inhibitor, in Mild-to-Moderate COVID-19: A Randomized, Comparative, Open-Label, Multicenter, Phase 3 Clinical Trial
Udwadia et al., International Journal of Infectious Diseases, doi:10.1016/j.ijid.2020.11.142
16 Nov 2020    Source   PDF   Share   Tweet
RCT with 75 favipiravir patients and 75 control patients showing reduced time to clinical cure and reduced time of viral shedding.
recovery time, 40.0% lower, relative time 0.60, p = 0.03, treatment 75, control 75.
time to viral-, 29.0% lower, relative time 0.71, p = 0.13, treatment 75, control 75.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Udwadia et al., 11/16/2020, Randomized Controlled Trial, India, South Asia, peer-reviewed, 11 authors.
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