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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality -19% Improvement Relative Risk Ventilation -53% ICU admission -19% c19favipiravir.com Solaymani-Dodaran et al. Favipiravir RCT LATE TREATMENT Favors favipiravir Favors lopinavir/ri..
Solaymani-Dodaran, 373 patient favipiravir late treatment RCT: 19% higher mortality [p=0.54], 53% higher ventilation [p=0.15], and 19% higher ICU admission [p=0.56] https://c19p.org/solaymanidodaran
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Safety and efficacy of Favipiravir in moderate to severe SARS-CoV-2 pneumonia
Solaymani-Dodaran et al., International Immunopharmacology, doi:10.1016/j.intimp.2021.107522
11 Mar 2021    Source   PDF   Share   Tweet
RCT late stage patients (median SpO2 89), 193 treated with favipiravir, 187 with lopinavir/ritonavir, showing no significant differences in mortality, intubation, or ICU admission.
risk of death, 19.2% higher, RR 1.19, p = 0.54, treatment 26 of 190 (13.7%), control 21 of 183 (11.5%).
risk of mechanical ventilation, 53.0% higher, RR 1.53, p = 0.15, treatment 27 of 190 (14.2%), control 17 of 183 (9.3%).
risk of ICU admission, 19.4% higher, RR 1.19, p = 0.56, treatment 31 of 190 (16.3%), control 25 of 183 (13.7%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Solaymani-Dodaran et al., 3/11/2021, Randomized Controlled Trial, Iran, Middle East, peer-reviewed, 44 authors, this trial compares with another treatment - results may be better when compared to placebo.
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Late treatment
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