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Favipiravir study #8 of 12
1/25 Early treatment study
Dabbous et al., Archives of Virology, doi:10.1007/s00705-021-04956-9 (Peer Reviewed)
Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study
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RCT with 44 favipiravir patients and 48 CQ patients, showing non-statistically significant lower mortality, ventilation, and hospitalization time with favipiravir.

Dabbous et al., 1/25/2021, Randomized Controlled Trial, Egypt, Middle East, peer-reviewed, 10 authors.
risk of death, 45.5% lower, RR 0.55, p = 0.12, treatment 1 of 44 (2.3%), control 2 of 48 (4.2%).
risk of mechanical ventilation, 88.5% lower, RR 0.12, p = 1.00, treatment 0 of 44 (0.0%), control 4 of 48 (8.3%), continuity correction due to zero event (with reciprocal of the contrasting arm).
hospitalization time, 16.4% lower, relative time 0.84, p = 0.06, treatment 44, control 48.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Details of all 12 studies
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