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Favipiravir study #1 of 12
3/18 Late treatment study
Cai et al., Engineering, doi:10.1016/j.eng.2020.03.007 (Peer Reviewed)
Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study
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Comparison of 35 FPV patients and 35 LPV/RTV patients, showing significant improvements in chest CT and faster viral clearance with FPV.

Cai et al., 3/18/2020, retrospective, China, Asia, peer-reviewed, 26 authors.
risk of no improvement in CT, 68.7% lower, RR 0.31, p = 0.04, treatment 35, control 45, multivariate.
risk of no virological cure, 70.9% lower, RR 0.29, p = 0.03, treatment 35, control 45, multivariate.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Details of all 12 studies
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