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Home   COVID-19 treatment studies for Favipiravir  COVID-19 treatment studies for Favipiravir  C19 studies: Favipiravir  Favipiravir   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ ICU admission -619% Improvement Relative Risk Hospitalization -219% Time to clinical improv.. -12% Time to viral clearance -15% primary c19favipiravir.com/bosaeed2.html Favors favipiravir Favors control
11 January 2022 - Early treatment study
Efficacy of favipiravir in adults with mild COVID-19: a randomized, double-blind, multicenter, placebo-controlled trial clinical trial
Bosaeed et al., Clinical Microbiology and Infection, doi:10.1016/j.cmi.2021.12.026 (Peer Reviewed)
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RCT with 112 favipiravir and 119 control patients showing no significant differences in outcomes. Viral clearance and clinical recovery for patients treated within 48 hours was better than those treated later. NCT04464408.
risk of ICU admission, 618.8% higher, RR 7.19, p = 0.11, treatment 3 of 112 (2.7%), control 0 of 119 (0.0%), continuity correction due to zero event (with reciprocal of the contrasting arm).
risk of hospitalization, 218.8% higher, RR 3.19, p = 0.16, treatment 6 of 112 (5.4%), control 2 of 119 (1.7%).
time to clinical improvement, 11.9% higher, RR 1.12, p = 0.51, treatment 112, control 119, adjusted per study.
time to viral clearance, 14.9% higher, RR 1.15, p = 0.51, treatment 112, control 119, adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Bosaeed et al., 1/11/2022, Double Blind Randomized Controlled Trial, Saudi Arabia, Middle East, peer-reviewed, 31 authors, study period 23 July, 2020 - 4 August, 2021, average treatment delay 3.0 days.
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