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0 0.5 1 1.5 2+ Mortality 7% Improvement Relative Risk ARDS -9% ICU time -34% Hospitalization time -37% c19favipiravir.com Al Mutair et al. Favipiravir for COVID-19 ICU Favors favipiravir Favors various
Al Mutair, 538 patient favipiravir late treatment study: 7% lower mortality [p=0.49], 9% higher ARDS [p=0.63], 34% higher ICU admission [p=0.001], and 37% longer hospitalization [p=0.001] https://c19p.org/almutair
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Overview of Clinical Outcome and Therapeutic Effectiveness of Favipiravir in Patients with COVID-19 Admitted to Intensive Care Unit, Riyadh, Saudi Arabia
Al Mutair et al., Journal of Infection and Public Health, doi:10.1016/j.jiph.2022.01.013
15 Feb 2022    Source   PDF   Share   Tweet
Retrospective 269 favipiravir ICU patients in Saudi Arabia and 269 matched controls receiving different treatments, showing no significant difference.
risk of death, 7.0% lower, RR 0.93, p = 0.49, treatment 119 of 269 (44.2%), control 128 of 269 (47.6%), NNT 30.
risk of ARDS, 8.6% higher, RR 1.09, p = 0.63, treatment 76 of 269 (28.3%), control 70 of 269 (26.0%), severe ARDS.
ICU time, 33.7% higher, relative time 1.34, p = 0.001, treatment 269, control 269.
hospitalization time, 36.6% higher, relative time 1.37, p = 0.001, treatment 269, control 269.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Al Mutair et al., 2/15/2022, retrospective, Saudi Arabia, Middle East, peer-reviewed, 14 authors, study period April 2020 - March 2021, this trial compares with another treatment - results may be better when compared to placebo.
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Late treatment
is less effective
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